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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RGS12 All Species: 17.88
Human Site: S667 Identified Species: 56.19
UniProt: O14924 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14924 NP_002917.1 1447 156357 S667 R S L D D L E S A T V S D G E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_850554 1417 153784 S667 R S L D D L E S A T V S D G E
Cat Felis silvestris
Mouse Mus musculus NP_775578 1381 149618 R660 S R R F S I T R S L D D L E S
Rat Rattus norvegicus O08774 1387 150450 S667 R S L D D L E S A T V S D G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520051 772 84545 F55 D P A G V R Y F S D F L R K E
Chicken Gallus gallus XP_420820 1393 153801 S660 R S L D D L E S A T V S D G E
Frog Xenopus laevis NP_001089606 766 84897 A50 D N S L S S N A S L P S V Q S
Zebra Danio Brachydanio rerio NP_999889 1540 169019 S692 R S L D D L E S A A V S D G E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 83 N.A. 79.5 79.2 N.A. 38.6 71.8 34 52.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. N.A. 88.4 N.A. 85.4 85.6 N.A. 43 82.7 41.3 64.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. N.A. 100 N.A. 0 100 N.A. 6.6 100 6.6 93.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 13.3 100 N.A. 13.3 100 26.6 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 0 0 0 13 63 13 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 0 0 63 63 0 0 0 0 13 13 13 63 0 0 % D
% Glu: 0 0 0 0 0 0 63 0 0 0 0 0 0 13 75 % E
% Phe: 0 0 0 13 0 0 0 13 0 0 13 0 0 0 0 % F
% Gly: 0 0 0 13 0 0 0 0 0 0 0 0 0 63 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % K
% Leu: 0 0 63 13 0 63 0 0 0 25 0 13 13 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 13 0 0 0 0 13 0 0 0 0 0 0 0 0 % N
% Pro: 0 13 0 0 0 0 0 0 0 0 13 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % Q
% Arg: 63 13 13 0 0 13 0 13 0 0 0 0 13 0 0 % R
% Ser: 13 63 13 0 25 13 0 63 38 0 0 75 0 0 25 % S
% Thr: 0 0 0 0 0 0 13 0 0 50 0 0 0 0 0 % T
% Val: 0 0 0 0 13 0 0 0 0 0 63 0 13 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _